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Kinmont Willie Armstrong (fl. 16th century), Scottish border reiver, known as "Kinmont Willie"

William Armstrong (artist) (1822-1914), Canadian artist

William Armstrong (Virginia) (1782-1865), U.S. Representative from Virginia

William Armstrong (Tennessee) (1795-1847), mayor of Nashville, Tennessee

William B. Armstrong, California state assembly member

William H. Armstrong (1914-1999), author of the children's book Sounder

William Hepburn Armstrong (1824-1919), U.S. Representative from Pennsylvania

William L. Armstrong (b. 1937), U.S. Senator from Colorado

William George Armstrong, 1st Baron Armstrong (1810-1900), British industrialist

William Armstrong, Baron Armstrong of Sanderstead (1915-1980), British civil servant

William Armstrong (bushranger), (1836-1859), Australian bushranger

William Armstrong, American automobile inventor and founder of Armstrong Electric