Weirdo was a magazine sized comics anthology created by Robert Crumb, published from 1981 to 1993 by Last Gasp. Weirdo served as an insistently "low art" counterpoint to its contemporary rival ''RAW'', Art Spiegelman and Françoise Mouly's highbrow alternative comics anthology. Early issues of Weirdo reflect Crumb's interests at the time – outsider art, fumetti, Church of the SubGenius-type anti-propaganda and assorted "weirdness". It also introduced artists such as Peter Bagge and Dennis (Stickboy) Worden.

Crumb later handed over the editing reins to Bagge, and then to Crumb's wife, cartoonist Aline Kominsky-Crumb. The last issue,

28, titled Verre D'eau, was published in 1993.