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    Tendonitis (also tenonitis or tendinitis) is an inflammation of a tendon. For example, patellar tendonitis (jumper's knee) is an inflammation of the patellar tendon, which connects the tibia to the patella.

    Chronic overuse of tendons leads to microscopic tears within the collagen matrix, which gradually weakens the tissue. Swelling in a region of microdamage or partial tear can be detected visually or by palpation. Increased water content and disorganised collagen matrix in tendon lesions may be detected by ultrasonography or magnetic resonance imaging.

    Due to their highly specialised ultrastructure and slow collagen turnover, tendons and ligaments are very slow to heal if injured, and rarely regain their original strength. Partial tears heal by the rapid production of disorganised type-III collagen, which is inferior in strength to normal tendon. Recurrence of injury in the damaged region of tendon is common.

    Recent research adds weight to a line of evidence suggesting that nitric oxide (NO) plays an important role in tendon healing (Xia ''et al'', 2006). And inhibition of NO synthesis impairs tendon healing (Darmani ''et al'', 2004). Such findings may lead to improved modes of treatment for this sometimes chronic condition. For example, NO is synthesized in the body from the amino acid arginine, supplementation of which boosts NO levels (UC Berkeley, Wellness Guide).

    Standard treatment of tendon injuries is largely palliative. Non-steroidal anti-inflammatory drugs combined with rest and gradual return to exercise is a common therapy. However, some evidence suggests that tendonitis is not an inflammatory disorder and that anti-inflammatory drugs are not effective (Khan ''et al'', 2002). Perhaps the most promising avenue of therapy is indicated in a line of research finding dramatic rates of recovery including complete remodeling of chronically damaged tendon tissue with eccentric loading exercise (see for example: Alfredson ''et al'' 1998; Mafi ''et al'', 2001; Fahlstrom ''et al'', 2003; Roos ''et al'', 2004; Öhberg ''et al'', 2004; Jonsson & Alfredson, 2005; Wilson & Best, 2005; Rees ''et al'', 2006).

    Preliminary research suggests that the injection of stem cells might promote tendon-injury healing (see: Future Treatments). Completely ruptured tendons may be sutured together with or without grafted material.

    Achilles tendonitis is a common injury, particularly in sports that involve lunging and jumping.

    A veterinary equivalent to Achilles tendonitis is bowed tendon, tendonitis of the superficial digital flexor tendon of the horse.

    Symptoms can vary from an achy pain and stiffness to the local area of the tendon, to a burning that surrounds the whole joint around the inflamed tendon. With this condition, the pain is usually worse during and after activity, and the tendon and joint area can become stiffer the following day.


        Tendonitis
            Common areas of tendon inflammation
            See also
    NamePAGENAME
    Diseasesdb31624
    Icd9ICD9
    Emedicinesubjemerg
    Emedicinetopic570
    MeshidD052256

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    Common areas of tendon inflammation

    The most common tendon areas that become inflamed are the elbow, wrist, forearm, biceps, shoulder (including rotator cuff attachments), leg, knee (patellar), ankle, hip, and Achilles. Of course, tendonitis will vary with each person, as it strikes the areas you use most. For example, many rock climbers tend to develop tendonitis in their fingers and swimmers in their shoulders (a.k.a. swimmer's shoulder.)

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    See also

     
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    This article is licensed under the GNU Free Documentation License [copyleft]. It uses material from the Wikipedia article "Tendonitis". link