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Spread (food), an edible paste put on other foods

the score difference being wagered on in spread betting

the measure of line inclination in rational trigonometry

In finance, the difference in price between related securities,

Bid/offer spread, between the buying and selling price of a commodity or security

Spread trade, between two related securities or commodities

Option adjusted spread, on mortgage backed securities where the borrower has the right to repay in full

Yield spread, difference in percentage rate of return of two instruments

Yield curve spread, on mortgage backed securities

Seafloor spreading, the process leading to continental drift

Spread spectrum, communications signals over a range of frequencies

Spread trader, holding positions in related securities, to trade the difference in price

Spread limit, a limit on a raise in poker

Spread polynomials, a polynomial sequence arising in rational trigonometry

$pread, a quarterly magazine by and for sex workers

"Spread", a song by OutKast from their 2003 album Speakerboxxx/The Love Below