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    The Spanish Flu Pandemic (less misleadingly called the 1918 flu pandemic) was a pandemic in 1918 and 1919 caused by an unusually severe and deadly strain of the subtype H1N1 of the species Influenza A virus (which apparently killed via cytokine storm, explaining the severe nature and unusual age distribution). In the 18 months of the pandemic, 50 million to 100 million people worldwide were killed. .

    Despite not having originated in Spain, the Allies of World War I came to call it the "Spanish Flu". This was mainly because the pandemic received greater press attention in Spain than in the rest of the world, as Spain was not involved in the war and there was no wartime censorship in Spain.

    The virus was believed to have died off after 18 months. However, recently (2006), scientists have used tissue samples from frozen victims to reproduce the virus for study.


        Spanish flu
            History
                Patterns of fatality
                Devastated communities
                Unaffected Locales
            Further reading

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    History
    The global mortality rate from the 1918/1919 pandemic is not known, but is estimated at 2.5 – 5% of the human population, with 20% of the world population suffering from the disease to some extent. Influenza may have killed as many as 25 million in its first 25 weeks; in contrast, AIDS killed 25 million in its first 25 years. Influenza spread across the world, killing more than 25 million in six months; some estimates put the total killed at over twice that number, possibly even 100 million.

    In the U.S., about 28% of the population suffered, and 500,000 to 675,000 died. In Britain 200,000 died; in France more than 400,000. Entire villages perished in Alaska and southern Africa. In Australia an estimated 10,000 people died and in the Fiji Islands, 14% of the population died during only two weeks, and in Western Samoa 22%. An estimated 17 million died in India, about 5% of India's population at the time. In the Indian Army, almost 22% of troops who caught the disease died of it.

    While World War I didn't cause the flu, the close quarters and mass movement of troops quickened its spread. It has been speculated that the soldiers' immune systems were weakened by the stresses of combat and chemical attacks, increasing their susceptibility to the disease.

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    Patterns of fatality
    The strain was unusual for influenza in that this pandemic killed many young adults and otherwise healthy victims - usual influenzas kill mostly newborns, the old, and the infirm.

    People without symptoms could be struck suddenly and within hours be too feeble to walk; many died the next day. Symptoms included a blue tint to the face and coughing up blood caused by severe obstruction of the lungs. In later stages, the virus caused an uncontrollable hemorrhaging that filled the lungs, and patients drowned in their body fluids.

    In fast-progressing cases, mortality was primarily from pneumonia, by virus-induced consolidation. Slower-progressing cases featured secondary bacterial pneumonias, and there may have been neural involvement that led to psychiatric disorders in a minority of cases. Some deaths resulted from malnourishment and even animal attacks in overwhelmed communities.

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    Devastated communities





    While in most places less than one-third of the population was infected and a fraction of that died, in a number of towns in several countries the entire population was wiped out.

    Even in areas where mortality was low, those incapacitated by the illness were often so numerous as to bring much of everyday life to a stop. Some communities closed all stores or required customers not to enter the store but place their orders outside the store for filling. There were many reports of places with no health care workers to tend the sick because of their own ill health and no able bodied grave diggers to bury the dead. Mass graves were dug by steam shovel and bodies buried without coffins in many places.


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    Unaffected Locales
    In Japan, 257,363 deaths were attributed to influenza by July 1919, giving an estimated 0.425% mortality rate, much lower than nearly all other Asian countries for which data are available. The Japanese government severely restricted maritime travel to and from the home islands when the plague struck. The only sizeable inhabited place with no documented outbreak of the flu in 1918–1919 was the island of Marajó at the mouth of the Amazon River in Brazil. In the Pacific, American Samoa
    and the French colony of New Caledonia

    also succeeded in preventing even a single death from influenza through effective quarantines.


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    Further reading


      Niall Johnson (2006) Britain and the 1918-19 Influenza Pandemic: A Dark Epilogue. Routledge, London and New York. ISBN 0-415-36560-0

      Terrence M. Tumpey, Adolfo García-Sastre, Andrea Mikulasova, Jeffery K. Taubenberger, David E. Swayne, Peter Palese, and Christopher F. Basler (2002) "Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus". Proceedings of the National Academy of Sciences 99, 13849–13854.

      Alfred W. Crosby (1990). America's Forgotten Pandemic: The Influenza of 1918. Cambridge University Press. ISBN 0-521-38695-0.

      John M. Barry, (2004). The Great Influenza: The Epic Story of the Greatest Plague in History. Viking Penguin. ISBN 0-670-89473-7.

      Andrew Noymer and Michel Garenne (2000). "The 1918 Influenza Epidemic's Effects on Sex Differentials in Mortality in the United States". Population and Development Review, 26(3):565–581.

      Geoffrey W. Rice and Edwina Palmer (1993). "Pandemic Influenza in Japan, 1918–19: Mortality Patterns and Official Responses". Journal of Japanese Studies, 19(2):389–420.

    Geoffrey W. Rice, Black November: the 1918 Influenza Pandemic in New Zealand , Canterbury University Press, 2005 ISBN 1-877257-35-4


     
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    This article is licensed under the GNU Free Documentation License [copyleft]. It uses material from the Wikipedia article "Spanish flu". link