Whaling was mentioned in Norwegian written sources as early as the year 800 and hunting Minke Whales with harpoons was common in the 11th century. In Western Norway, Minkes were trapped in bays and coves and killed with the help of bacteria infected arrows, a form of whaling that continued up until the 20th century.

By the end of the 1930s they were the target of coastal whaling from countries including Brazil, Canada, China, Greenland, Japan, Korea, Norway, and South Africa. Minke Whales were not then regularly hunted by the large-scale whaling operations in the Southern Ocean on account of their relatively small size. However, by the early 1970s, following the over-hunting of larger whales such as the Sei, Fin, and Blue Whales, Minkes attracted the attention of these whalers too. By 1979 the Minke was the only whale caught by Southern Ocean fleets. Hunting continued apace until the general moratorium on whaling was introduced in 1986. According to a study by the International Whaling Commission, 116,568 Minke Whales were caught by whalers between 1904 and 2000. Around 100,000 of these were killed in the Southern Ocean.

Following the moratorium, most hunting of Minke Whales ceased. Japan and more recently Iceland (in August 2003) have continued hunting for Minkes on scientific grounds, however, these "scientific grounds" are criticised by many organisations as being a cover for commercial whaling. Both Iceland and Japan have the long term goal of resuming open commercial whaling. Although Norway initially followed the moratorium, they placed an objection to it with the IWC and resumed a commercial hunt in 1993. Norwegian whalers caught 639 in 2005. The quota for 2006 was set at 1052 animals, from which a catch of 521 was taken. *