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    White blood cells or leukocytes are cells which form a component of the blood. They are produced in the bone marrow and help to defend the body against infectious disease and foreign materials as part of the immune system. There are normally between 4x109 and 11x109 white blood cells in a litre of healthy adult blood — about 7,000 to 25,000 white blood cells per drop. In conditions such as leukaemia this may rise to as many as 50,000 white blood cells in a single drop of blood. As well as in the blood, white cells are also found in large numbers in the lymphatic system, the spleen, and in other body tissues.


        White blood cell
            Nomenclature
            Types
            Diseases
            Other tissue cells
            See also

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    Nomenclature
    The name "white cells" derives from the fact that after centrifugation of a blood sample, the white cells are found in the Buffy coat, a thin layer of nucleated cells between the sedimented red blood cells and the blood plasma, which is white in color (or sometimes green, if there are large amounts of neutrophils in the sample, which are high in green myeloperoxidase).A drop of blood can contain from anywhere from 7000 to 25000 white blood cells

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    Types
    There are many different types of white blood cells. One primary technique to classify them is to look for the presence of granules, which produces the categories "granulocytes" and "agranulocytes".

      Granulocytes: As Granular Leukocytes and polymorphonuclear leucocytes (informally, "PMNS" or "Polys"), Granulocytes are a category of white blood cells, characterised by the fact that all types have differently staining granules in their cytoplasm on light microscopy. These granules are related to lysosomes found in some regular cells and primarily act in the digestion of engulfed invaders. There are three types of granulocytes: neutrophils, basophils, and eosinophils (named according to their staining properties).

      Agranulocytes: Agranulocytes are a category of white blood cells which are characterised by the absence of granules in their cytoplasm. There are two types of agranulocytes: lymphocytes and monocytes.

    These categories can be further broken down as follows:



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    Diseases
      Leukopenia is a disease symptom defined as a lower than normal number of white blood cells in the blood.
      Leukocytosis refers to an increase in the number of white blood cells in the blood.

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    Other tissue cells
      Histiocytes, found in the lymphatic system and other body tissues, but not normally in blood:
      Allergies can also change your white blood cell count.

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    See also
     
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    This article is licensed under the GNU Free Documentation License [copyleft]. It uses material from the Wikipedia article "White blood cell". link