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Landing Ship, Medium, a form of amphibious assault ship

"Laser Scanning Microscopy" (see Confocal laser scanning microscopy), a type of microscopy in which laser light is used for illumination

Layered synthetic microstructure, a diffracting medium in long wavelength X-ray spectrometry

The Lesbian Sex Mafia, a women-only BDSM organization

Linear Synchronous Motor

Linux Security Modules, a project providing a lightweight, general purpose framework for access control on Linux

Linux Software Map, a standard text format for describing Linux software

Living Stream Ministry, the non-profit publisher

Lourdes School of Mandaluyong, a private Catholic institute of learning in Metro Manila, the Philippines

Lutheran Student Movement, a pan-Lutheran student led organization active at the local, regional, and national level

image files produced by the Zeiss LSM line of confocal microscopes

text files in the Linux Software Map format