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Hyperion (mythology), Titan from Greek mythology

Hyperion (moon), moon of Saturn

Hyperion (album), album by power metal band Manticora

Hyperion (poem), unfinished epic poem by John Keats

Hyperion (Longfellow), book by Henry Wadsworth Longfellow

Hyperion (Hölderlin), a novel by Friedrich Hölderlin

Hyperion (journal), short-lived 1908 German literary journal

Hyperion (novel), science fiction novel by Dan Simmons, in his Hyperion Cantos series

Hyperion class (Babylon 5), class of heavy cruisers in the Babylon 5 universe

Hyperion (comics), various Marvel Comics characters

Hyperion (Supreme Power), one such Marvel Comics character

Hyperion (StarCraft), a battlecruiser in the StarCraft universe

Gradius video game series (Hyperion used as a name in the MSX installments)

Hyperion Hotel, office in the Angel TV series.

Emperor Hyperion, villain in the Gekigangar 3

Hyperion, an alien world over eleven million light-years away from Earth on seaQuest DSV.

Hyperion, robotic unit in Empire Earth

Hyperion, Seifer Almasy's gunblade

CAT1-X Hyperion Gundam series fictional weapon

Hyperion Blacksmith, a red creature from the card game Magic: The Gathering from the expansion Legends.

Hyperion Solutions Corporation, business software maker

Hyperion Entertainment, games software maker

Hyperion Records, classical record label

Hyperion (publisher), a book publishing division of Disney Corporation

Consult Hyperion, a consultancy specializing in secure transactions

HMS Hyperion (H97) (1936-1940), British warship

Hyperion (computer), Canadian computer from the 1980s

Hyperion sewage treatment plant, large Los Angeles sewage treatment plant

hyperion-ircd, the IRCd used and maintained by the freenode network.

Hyperion (horse), British racehorse.

Hyperion (instrument), instrument on board the EO-1 satellite.

Hyperion (tree), a redwood tree that is the tallest living tree.