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H2 receptors positively coupled to adenylate cyclase via Gs. It is a potent stimulant of cAMP* production. It increases the intracellular Ca2+ concentrations and release Ca2+ from intracellular stores. The drug Betazole is an example of a Histamine H2 receptor agonist.
Location Response H see H2-receptor agonist and H2-receptor antagonist | ||||||||
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