George Cabot (December 3, 1752–April 18, 1823), was an American merchant, seaman, and politician from Boston, Massachusetts. He represented Massachusetts in the U.S. Senate and as the Presiding Officer of the Hartford Convention.

Cabot was born in Salem, Massachusetts, and attended Harvard College for two years before dropping out to go to sea. By the age of twenty-one he was captain of his own ship.

A member of the Pro-Administration Party and a Federalist, Cabot's political career began in 1775 and lasted until he became a delegate to the Hartford Convention of 1814. He died in Boston, Massachusetts in 1823 and was interred in the Mount Auburn Cemetery in Cambridge, Massachusetts.