The Frankfurt Rhine Main Area, often referred to as Rhine Main Area (German: Rhein-Main Gebiet) or Greater Frankfurt is a Metropolitan Area located in central western Germany, that encompasses parts of three federal states: Hesse, Rhineland-Palatinate and Bavaria. It contains the cities Frankfurt, Wiesbaden, Offenbach, Mainz, and Darmstadt.

The polycentric region is named after its core city Frankfurt and the rivers Rhine and Main. The Frankfurt Rhine Main Area, as officially designated as a European Metropolitan Area by Germany's Federal Office for Building and Regional Planning, has a population exceeding 5.2 million and covers an area of roughly 13,000 km².