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A drug overdose occurs when a drug is ingested in quantities and/or concentrations large enough to overwhelm the homeostasis of a living organism, causing severe illness or death. It is a type of poisoning.
Types The word "overdose" implies that there is a safe dosage and therefore the term overdose is commonly only applied to drugs, not poisons. Drug overdoses are sometimes caused intentionally to commit suicide, but many drug overdoses are accidental and are usually the result of either irresponsible behavior (such as overindulging at a party), or the misreading of product labels. Other causes of overdose (especially heroin) include multiple drug use with counter indications (cocaine/amphetamines/alcohol) or use after a period of abstinence. A common unintentional overdose in young children involves multi-vitamins containing iron. Iron is a component of the hemoglobin molecule in blood, used to transport oxygen to living cells. When taken in small amounts, iron allows the body to replenish hemoglobin, but in large amounts it causes severe pH imbalances in the body. If this overdose is not treated with chelation therapy, it can lead to death or permanent coma. Symptoms Symptoms of overdose occur in various forms: Diagnosis Diagnosis of an overdosed patient is generally straightforward if the drug is known. However, it can be very difficult if the patient cannot (or refuses to) state what drug they have overdosed on. At times, certain symptoms and signs exhibited by the patient, or blood tests, can reveal the drug in question. Even without knowing the drug, most patients can be treated with general supportive measures. In some instances, empirical antidotes may be administered if there is sufficient indication that the patient has overdosed on a particular type of medication: naloxone in opioids and flumazenil in benzodiazepines. Rapid reversal of symptoms may serve as proof in these cases. First aid Depressants First aid can prevent a death from overdose of depressants as it may take several hours for someone to die in these cases. The common drugs in this category include opiates ( ie. heroin, morphine and methadone), alcohol, and certain prescription drugs such as benzodiazepines. Signs of overdose are those of a depressed central nervous system — slow, infrequent or shallow breathing, blue lips or fingernails, cold or pale skin, slow or faint pulse, snoring or gurgling noises, and the inability to be woken from nodding off. Stimulants People can overdose on stimulants, such as amphetamines, ecstasy and cocaine, too, with symptoms such as rapid heartbeat, muscle cramps, seizures, paranoia, psychosis, confusion, loss of control of movement, vomiting and lack of consciousness. First aid in these cases involves staying with the person and helping them to remain calm. Move them to a quiet area, and where possible, apply a wet cloth to their neck or forehead. If unconscious, place them in the recovery position and call an ambulance. Prevention Causes Common types of drugs that are overdosed on: See also | ||||||||
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