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Phosphocreatine, also known as creatine phosphate or PCr, is a phosphorylated creatine molecule that is an important energy store in skeletal muscle. It is used to generate ATP from ADP, forming creatine for the 2 to 7 seconds following an intense effort. This reaction is reversible and it therefore acts as a spatial and temporal buffer of ATP concentration. Phosphocreatine plays a particularly important role in tissues that have high, fluctuating energy demands such as muscle and brain.Creatine phosphate is synthesized in the liver, and transported to the muscle cells for storage.
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