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Bufotoxins are a family of toxic substances found in the parotoid glands, skin and venom of many toads (genus Bufo); other amphibians; and other plants and mushrooms (Siperstein et al, 1957; Lincoff & Mitchel, 1977; Kibmer & Wichtl, 1986). The exact composition varies greatly with the specific source of the toxin. It can contain: 5-MeO-DMT, bufagins, bufotalin, bufotenine, bufothionine, epinephrine, norepinephrine, and serotonin. The term bufotoxin can also be used specifically to describe the conjugate of a bufagin with suberylargine (Chen & Kovarikova, 1967).
Extract from the skin of certain Asian toads, such as Bufo gargarizans, is often found in certain Chinese folk remedies.
Toads known to secrete bufotoxin are:
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