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Ab urbe condita, Latin for "from the founding of the city (of Rome), used for calculation of dates. (Also as Anno Urbis Conditae, "in the year from the founding of the city.)

Atlanta University Center

United Self-Defense Forces of Colombia (in Spanish: Autodefensas Unidas de Colombia), the main paramilitary group in Colombia

Area under the curve (plasma drug concentration-time curve) in Medicine and Pharmacology

Authentication Center in a GSM mobile phone network

American University in Cairo

Atlantic Union College

Aalborg University was formerly called Aalborg Universitetscenter, and used AUC as the official abbreviation.

A user community used by Montgomery Blair High School in Silver Spring, Maryland to track assignments and classes.

American University in Cairo

Apple University Consortium in Australia

Alliance University College in Alberta

American University of the Caribbean a medical school in St. Maarten