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529 BC - Cambyses II started to rule. He is son of Cyrus II. He conquered Egypt and Cyprus.

528 BC - Gautama Buddha attained Enlightenment, and began his ministry.

526 BC - Psammetichus III succeeds Amasis II as king of Egypt.

525 BC - Cambyses II, ruler of Persia, conquers Egypt, defeating Psammetichus III. This is considered the end of the Twenty-sixth Dynasty, and the start of the Twenty-seventh Dynasty.

c. 525 BC - Coins started to have an image on two sides.

522 BC - Smerdis succeeds Cambyses II as ruler of Persia.

522 BC - Babylon rebels against Persian rule.

521 BC - Darius I succeeds Smerdis as ruler of Persia. He is son of a government official.

521 BC - The Babylonian rebellion against Persian rule is suppressed.

520 BC - Zhou dao wang becomes King of the Zhou Dynasty of China but dies before the end of the year.

520 BC - Cleomenes I succeeds Anaxandridas as king of Sparta. (approximate date).

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525 BC - Aeschylus, author of Greek tragedies (d. 456 BC).

522 BC - Pindar, Greek poet.

520 BC - Panini, Hindu Indian grammarian (d. 460 BC).

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July, 529 BC - Cyrus the Great, ruler of ancient Persia

527 BC - Mahavira, major Jain reformist (b. 599 BC).

527 BC - Pisistratus, Athenian general.

525 BC - Anaximenes of Miletus, Greek philosopher (born 585 BC).

525 BC - Psammetichus III, the last Pharaoh of the Twenty-sixth Dynasty of Egypt.

March, 521 BC - Cambyses II, ruler of ancient Persia (suicide).

October, 521 BC - Smerdis, ruler of ancient Persia.